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Bioinformatics- Basics


What is bioinformatics? it is Biology + Information  

Need an easy answer?

Bioinformatics is a branch of science which uses computers to solve molecular biology problems.

Thinking about a tough Answer?

Bioinformatics is an application of information Technology to the field of Molecular Biology for management and analysis of biological data and knowledge. A Subset of Computational Biology. It entails creation and advancement of databases, Algorithms, Computational and statistical techniques.

For a Bioinformatician    

  • Computer is Laboratory
  • Computational Tools are Equipments
  • Database is Test Animals/Chemicals

Why Bioinformatics?

We are experiencing an unparalleled boom in the already significant biotechnology and pharmaceutical industries.  Computational methods are necessary to analyze the Massive amount of information that are coming out of the genome projects.  To study how normal cellular activities are altered in different disease states, the biological data must be combined to form a comprehensive picture of these activities.  Bioinformatics allows analyzing huge amount of biological data and induces the advancement of biomedicine. Bioinformatics will provide new insights into biological functions and Bioinformatics techniques have reinforced that, simple organisms are models for more complex systems, DNA and protein similarities illustrate evolutionary history, Gene varioations in populations are important for drug discovery, speed up drug discovery pipeline and genetic data has important personal and social implications.

Most pressing tasks in Bioinformatics 

Currently the most calling tasks in this area involves, analysis and interpretation of various types of data,including nucleotide and amino acid sequences, protein domains and protein structures.

Major Research Areas :

  • The development and implementation of tools that enable efficient access, management of  various types of information
  • Development of new algorithms
  • Generating Methods to locate a gene within a sequence
  • Identifying protein structure and/or function
  • Predicting Protein-Protein Interactions
  • clustering protein sequences into families of related sequences

Topics coming under Bioinformatics :

  • Computational Biology
  • Post-Genome Applications
  • Bioinformatics and medicine
  • Bioinformatics and biodiversity
  • Bioengineering
  • Gene Expression
  • Gene Network
  • Sequence Analysis
  • Structure Network
  • Molecular Evolution